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Showing search results for "Blood Vessel"

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Papers Institution Country Funding

Alitalo, Kari

426 23 University of Helsinki Finland -

Carmeliet, P

256.3 17 Vesalius Research Center, KU Leuven, Leuven Belgium -

Detmar, Michael

250.3 26 Swiss Federal Institute of Technology Switzerland $155,925.00

Jain, Rakesh K

176.9 14 Massachusetts General Hospital and Harvard Medical School USA $27,849,572.00

Ferrara, Napoleone

166.5 17 Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 USA -

Koh, Gou Young

161.2 11 Korea Advanced Institute of Science and Technology Korea -

Cao, Yihai

156.6 16 Karolinska Institute Sweden -

McDonald, Donald M

146.5 15 University of California USA $4,413,923.00

Kahn, Mark L

117.5 6 University of Pennsylvania USA $10,106,623.00

Adams, Ralf H

117.1 5 Cancer Research UK London Research Institute UK -

Johnson, Randall S

94.4 7 University of California USA -

Ylä-Herttuala, S

88 19 University of Eastern Finland Finland -

Zhang, Yun

87.8 22 Shandong University China $3,191,119.00

Mercurio, Arthur M

87.1 5 University of Massachusetts Medical School USA $5,785,281.00

Choueiri, Toni K

85.8 8 Stanford University School of Medicine USA -

Simons, Michael

79.8 7 Yale University School of Medicine USA $16,608,443.00

Popel, Aleksander S

77.2 16 Johns Hopkins University School of Medicine USA $7,879,505.00

Petrova, Tatiana V

74.5 4 Molecular and Cancer Biology Program, Biomedicum Helsinki, Helsinki Finland -

Stacker, Steven A

72.8 5 Royal Melbourne Hospital Australia -

Ambati, Jayakrishna

71.7 2 Departments of Ophthalmology & Visual Sciences, Lexington, Kentucky USA $7,853,201.00

Hodivala-Dilke, Kairbaan M

71.3 7 Bart's & The London Queen Mary's School of Medicine & Dentistry UK -

Luo, Yongzhang

70.5 11 Tsinghua University China -

Ruhrberg, Christiana

70.4 10 University College London UK -

Van Cutsem, Eric

67.1 4 University of Chicago Comprehensive Cancer Center USA -

Ellis, Lee M

64.9 7 The University of Texas MD Anderson Cancer Center USA $1,977,594.00

Ribatti, Domenico

64.9 16 University of Bari Medical School Italy -

Fu, Yang-Xin

64.9 1 Chinese Academy of Sciences China $6,786,107.00

D'Amore, Patricia A

61.6 12 Schepens Eye Research Institute/Massachusett Eye and Ear USA -

Chen, Xiaoyuan

60.9 12 Stanford University School of Medicine USA $14,363,192.00

Schwartz, Martin A

58.6 2 N/A $9,451,470.00

Heymach, John V

58.1 6 The University of Texas M. D. Anderson Cancer Center USA $848,140.00

Kiefer, Friedemann

57.8 3 Max Planck Institute for Molecular Biomedicine Germany -

Dai, Jianwu

57.6 9 Chinese Academy of Sciences China -

Hong, Yong-Kil

56.9 5 The Catholic University of Korea Korea -

Oliver, Guillermo

56.5 4 Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 USA $5,733,624.00

Punt, Cornelis J A

55.6 2 Radboud University Nijmegen Medical Center Netherlands -

Kerbel, Robert S

55.6 3 University of Toronto USA $962,085.00

Dvorak, Harold F

53.9 8 Harvard Medical School USA -

Brady, Mark F

53.3 1 Fox Chase Cancer Center USA -

Gilman, Andrew L

53.3 1 and Moores Cancer Center USA -

Komatsu, Masanobu

53.1 1 Sanford-Burnham Medical Research Institute at Lake Nona USA $2,193,064.00

Lammert, Eckhard

52.6 5 Heinrich-Heine-University Germany -

Motzer, Robert J

52.5 5 Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 USA $1,377,352.00

Liu, Mingyao

50.3 8 East China Normal University China $1,661,352.00

Yoon, Young-sup

49.2 2 Emory University School of Medicine USA $9,568,558.00

Lemström, Karl B

49.1 2 FI-00014 University of Helsinki and Helsinki University Central Hospital Finland -

Wang, Yizheng

48.9 14 Second Military Medical University China -

Mooney, David J

47.8 6 Harvard University USA $13,796,290.00

Bautch, Victoria L

47.5 6 The University of North Carolina at Chapel Hill USA $3,977,091.00

Sood, Anil K

46.7 5 University of Texas M.D. Anderson Cancer Center USA $21,735,597.00
Name Institution Date Impact Publication

Brady, Mark F

Fox Chase Cancer Center 12/29/2011 53.29 The New England journal of medicine
Incorporation of bevacizumab in the primary treatment of ovarian cancer. Abstract

Gilman, Andrew L

and Moores Cancer Center 09/30/2010 53.29 The New England journal of medicine
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. Abstract

Punt, Cornelis J A

Radboud University Nijmegen Medical Center 02/06/2009 53.29 The New England journal of medicine
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. Abstract

Alitalo, Kari

University of Helsinki 02/23/2009 39.12 Nature reviews. Molecular cell biology
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Abstract

Schwartz, Martin A

University of Virginia 02/06/2009 39.12 Nature reviews. Molecular cell biology
Mechanotransduction in vascular physiology and atherogenesis. Abstract

Motzer, Robert J

Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 11/04/2011 38.27 Lancet
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Abstract

Mercurio, Arthur M

University of Massachusetts Medical School 11/22/2013 37.54 Nature reviews. Cancer
VEGF targets the tumour cell. Abstract

McDonald, Donald M

University of California 09/24/2012 37.54 Nature reviews. Cancer
Controlling escape from angiogenesis inhibitors. Abstract

Adams, Ralf H

Cancer Research UK London Research Institute 03/18/2012 36.28 Nature
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Abstract

Adams, Ralf H

Cancer Research UK London Research Institute 06/01/2010 36.28 Nature
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 09/17/2009 36.28 Nature
VEGFR1-activity-independent metastasis formation. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 03/04/2013 32.40 Cell
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 04/07/2010 32.40 Cell
PlGF blockade does not inhibit angiogenesis during primary tumor growth. Abstract

Carmeliet, Peter

University of Leuven 04/07/2010 32.40 Cell
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Abstract

Alitalo, Kari

University of Helsinki 02/24/2010 32.40 Cell
Lymphangiogenesis: Molecular mechanisms and future promise. Abstract

Carmeliet, Peter

University of Leuven 04/03/2009 26.86 Physiological reviews
Role and therapeutic potential of VEGF in the nervous system. Abstract

Kahn, Mark L

University of Pennsylvania 07/12/2013 26.56 Cancer cell
Platelets and tumor cells: a new form of border control. Abstract

Komatsu, Masanobu

Sanford-Burnham Medical Research Institute at Lake Nona 08/17/2012 26.56 Cancer cell
Small GTPase R-Ras regulates integrity and functionality of tumor blood vessels. Abstract

Stacker, Steven A

Royal Melbourne Hospital 02/20/2012 26.56 Cancer cell
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium. Abstract

Johnson, Randall S

University of California 01/23/2012 26.56 Cancer cell
Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success. Abstract

Carmeliet, Peter

University of Leuven 06/13/2011 26.56 Cancer cell
Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Abstract

Carmeliet, Peter

University of Leuven 01/06/2011 26.56 Cancer cell
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Abstract

McDonald, Donald M

University of California 12/15/2010 26.56 Cancer cell
New antibody to stop tumor angiogenesis and lymphatic spread by blocking receptor partnering. Abstract

Alitalo, Kari

University of Helsinki 12/02/2010 26.56 Cancer cell
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 08/16/2010 26.56 Cancer cell
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage. Abstract

Sood, Anil K

University of Texas M.D. Anderson Cancer Center 08/16/2010 26.56 Cancer cell
Regulation of tumor angiogenesis by EZH2. Abstract

Johnson, Randall S

University of California 06/14/2010 26.56 Cancer cell
Tumor vessels are Eph-ing complicated. Abstract

Mercurio, Arthur M

University of Massachusetts Medical School 04/13/2010 26.56 Cancer cell
ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Abstract

Carmeliet, Peter

University of Leuven 03/02/2009 26.56 Cancer cell
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Abstract

Kerbel, Robert S

University of Toronto 03/02/2009 26.56 Cancer cell
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Abstract

Kerbel, Robert S

University of Toronto 12/29/2008 26.56 Cancer cell
Tumor-associated fibroblasts as "Trojan Horse" mediators of resistance to anti-VEGF therapy. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 12/29/2008 26.56 Cancer cell
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Abstract

Choueiri, Toni K

Stanford University School of Medicine 08/08/2012 22.58 The Lancet. Oncology
Conditional survival of patients with metastatic renal-cell carcinoma treated with VEGF-targeted therapy: a population-based study. Abstract

Van Cutsem, Eric

University of Chicago Comprehensive Cancer Center 05/17/2012 22.58 The Lancet. Oncology
VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials. Abstract

Van Cutsem, Eric

University of Chicago Comprehensive Cancer Center 03/07/2011 22.58 The Lancet. Oncology
Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study. Abstract

Ellis, Lee M

The University of Texas MD Anderson Cancer Center 02/18/2010 22.58 The Lancet. Oncology
Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 08/04/2013 22.46 Nature medicine
An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Abstract

Alitalo, Kari

University of Helsinki 11/07/2011 22.46 Nature medicine
The lymphatic vasculature in disease. Abstract

Ambati, Jayakrishna

Departments of Ophthalmology & Visual Sciences, Lexington, Kentucky 08/09/2009 22.46 Nature medicine
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 03/22/2009 22.46 Nature medicine
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. Abstract

Kahn, Mark L

University of Pennsylvania 01/18/2009 22.46 Nature medicine
Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Abstract

Fu, Yang-Xin

Chinese Academy of Sciences 01/28/2011 21.63 Immunity
Deflating the lymph node. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 01/20/2011 21.63 Immunity
T lymphocytes negatively regulate lymph node lymphatic vessel formation. Abstract

Adams, Ralf H

Cancer Research UK London Research Institute 01/27/2013 19.48 Nature cell biology
Spatial regulation of VEGF receptor endocytosis in angiogenesis. Abstract

Schwartz, Martin A

10/03/2012 19.48 Nature cell biology
Profilin phosphorylation as a VEGFR effector in angiogenesis. Abstract

Alitalo, Kari

University of Helsinki 09/11/2011 19.48 Nature cell biology
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling. Abstract

Van Cutsem, Eric

University of Chicago Comprehensive Cancer Center 09/10/2012 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Cediranib with mFOLFOX6 versus bevacizumab with mFOLFOX6 as first-line treatment for patients with advanced colorectal cancer: a double-blind, randomized phase III study (HORIZON III). Abstract

Choueiri, Toni K

Stanford University School of Medicine 02/06/2012 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 05/10/2010 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. Abstract

Heymach, John V

The University of Texas M. D. Anderson Cancer Center 11/30/2009 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Distinct patterns of cytokine and angiogenic factor modulation and markers of benefit for vandetanib and/or chemotherapy in patients with non-small-cell lung cancer. Abstract

Choueiri, Toni K

Stanford University School of Medicine 10/13/2009 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 03/30/2009 18.37 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. Abstract

Alitalo, Kari

University of Helsinki 01/29/2013 14.73 Circulation
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis. Abstract

Hong, Young-Kwon

University of Southern California 01/24/2012 14.73 Circulation
9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Abstract

Ruhrberg, Christiana

University College London 06/10/2011 14.73 Neuron
VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Abstract

Carmeliet, Peter

University of Leuven 06/10/2011 14.73 Neuron
VEGF mediates commissural axon chemoattraction through its receptor Flk1. Abstract

Alitalo, Kari

University of Helsinki 10/11/2010 14.73 Circulation
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation. Abstract

Yoon, Young-sup

Emory University School of Medicine 09/20/2010 14.73 Circulation
Podoplanin-expressing cells derived from bone marrow play a crucial role in postnatal lymphatic neovascularization. Abstract

Lemström, Karl B

FI-00014 University of Helsinki and Helsinki University Central Hospital 03/15/2010 14.73 Circulation
Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts. Abstract

Dai, Jianwu

Chinese Academy of Sciences 03/23/2009 14.73 Circulation
Collagen-targeting vascular endothelial growth factor improves cardiac performance after myocardial infarction. Abstract

Simons, Michael

Yale University School of Medicine 05/03/2013 14.03 Developmental cell
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Abstract

Petrova, Tatiana V

University of Helsinki 02/02/2012 14.03 Developmental cell
Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation. Abstract

Simons, Michael

Yale University School of Medicine 05/06/2010 14.03 Developmental cell
VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Abstract

Kiefer, Friedemann

Max Planck Institute for Molecular Biomedicine 03/16/2010 14.03 Developmental cell
Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Abstract

Lammert, Eckhard

Heinrich-Heine-University of Düsseldorf 10/26/2009 14.03 Developmental cell
The molecular basis of vascular lumen formation in the developing mouse aorta. Abstract

Johnson, Randall S

University of California 06/17/2009 14.03 Developmental cell
You don't need a PHD to grow a tumor. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 09/13/2010 13.85 The Journal of experimental medicine
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 05/13/2013 13.75 Journal of the National Cancer Institute
Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions. Abstract

Alitalo, Kari

University of Helsinki 02/17/2012 13.75 Journal of the National Cancer Institute
Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis. Abstract

Carmeliet, Peter

University of Leuven 12/12/2013 13.66 Cell metabolism
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis. Abstract

Carmeliet, Peter

University of Leuven 08/22/2013 13.66 Cell metabolism
Role of endothelial cell metabolism in vessel sprouting. Abstract

Mooney, David J

Harvard University 12/30/2010 13.19 Nano letters
Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Abstract

Kahn, Mark L

University of Pennsylvania 02/12/2014 13.06 The Journal of clinical investigation
Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. Abstract

Carmeliet, Peter

University of Leuven 08/01/2013 13.06 The Journal of clinical investigation
Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer. Abstract

Simons, Michael

Yale University School of Medicine 02/08/2013 13.06 The Journal of clinical investigation
Endothelial ERK signaling controls lymphatic fate specification. Abstract

Kahn, Mark L

University of Pennsylvania 05/24/2012 13.06 The Journal of clinical investigation
Blood flow reprograms lymphatic vessels to blood vessels. Abstract

Simons, Michael

Yale University School of Medicine 07/11/2011 13.06 The Journal of clinical investigation
FGF-dependent regulation of VEGF receptor 2 expression in mice. Abstract

Alitalo, Kari

University of Helsinki 05/23/2011 13.06 The Journal of clinical investigation
The yin, the yang, and the angiopoietin-1. Abstract

Heymach, John V

The University of Texas M. D. Anderson Cancer Center 03/23/2011 13.06 The Journal of clinical investigation
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. Abstract

McDonald, Donald M

University of California-San Francisco 09/14/2009 13.06 The Journal of clinical investigation
TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. Abstract

Simons, Michael

Yale University School of Medicine 02/25/2012 12.89 Current opinion in cell biology
VEGF signaling inside vascular endothelial cells and beyond. Abstract

Adams, Ralf H

Cancer Research UK London Research Institute 10/04/2010 12.89 Current opinion in cell biology
Dynamics of endothelial cell behavior in sprouting angiogenesis. Abstract

Lammert, Eckhard

Heinrich-Heine-University 08/02/2010 12.89 Current opinion in cell biology
Resolving cell-cell junctions: lumen formation in blood vessels. Abstract

Alitalo, Kari

University of Helsinki 02/21/2009 12.89 Current opinion in cell biology
VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Abstract

Ellis, Lee M

The University of Texas MD Anderson Cancer Center 02/14/2012 11.96 Nature reviews. Clinical oncology
Antiangiogenic therapy--evolving view based on clinical trial results. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 03/08/2011 11.96 Nature reviews. Clinical oncology
HCC and angiogenesis: possible targets and future directions. Abstract

Oliver, Guillermo

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 10/20/2011 11.65 Genes & development
Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Abstract

Oliver, Guillermo

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 10/04/2010 11.65 Genes & development
Current views on the function of the lymphatic vasculature in health and disease. Abstract

Alitalo, Kari

University of Helsinki 05/04/2010 11.65 Genes & development
Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Abstract

Oliver, Guillermo

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 04/02/2010 11.65 Genes & development
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 11/25/2009 10.92 Trends in pharmacological sciences
Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 12/07/2010 10.47 European heart journal
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 05/12/2012 10.40 Trends in immunology
Regulation and implications of inflammatory lymphangiogenesis. Abstract

Alitalo, Kari

University of Helsinki 04/12/2011 10.35 Trends in molecular medicine
VEGF and angiopoietin signaling in tumor angiogenesis and metastasis. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 08/02/2013 10.33 EMBO molecular medicine
VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. Abstract

Mercurio, Arthur M

University of Massachusetts Medical School 02/21/2013 10.33 EMBO molecular medicine
GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 12/14/2010 10.33 EMBO molecular medicine
Endothelial FAK is required for tumour angiogenesis. Abstract

Petrova, Tatiana V

University of Helsinki 05/17/2011 10.26 The Journal of cell biology
Lymphatic vascular morphogenesis in development, physiology, and disease. Abstract

Petrova, Tatiana V

University of Helsinki 04/27/2009 10.26 The Journal of cell biology
FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. Abstract

Lammert, Eckhard

Heinrich-Heine University 10/11/2012 9.92 Nature protocols
Pharmacological manipulation of blood and lymphatic vascularization in ex vivo-cultured mouse embryos. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 03/22/2012 9.92 Nature protocols
An isolated tumor perfusion model in mice. Abstract

Cao, Yihai

Karolinska Institute 05/19/2011 9.92 Nature protocols
Mouse corneal lymphangiogenesis model. Abstract

Cao, Yihai

Karolinska Institute 11/04/2010 9.92 Nature protocols
Hypoxia-induced metastasis model in embryonic zebrafish. Abstract

Ruhrberg, Christiana

University College London 01/11/2013 9.90 Blood
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 08/14/2012 9.90 Blood
ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Abstract

Oliver, Guillermo

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 08/02/2012 9.90 Blood
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 06/16/2011 9.90 Blood
Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Abstract

Alitalo, Kari

University of Helsinki 05/12/2011 9.90 Blood
Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor. Abstract

Luo, Yongzhang

Tsinghua University 04/11/2011 9.90 Blood
Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 03/01/2011 9.90 Blood
An important role of lymphatic vessel activation in limiting acute inflammation. Abstract

Alitalo, Kari

University of Helsinki 12/08/2010 9.90 Blood
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity. Abstract

Hong, Young-Kwon

University of Southern California 10/20/2010 9.90 Blood
Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 08/17/2010 9.90 Blood
Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 07/27/2010 9.90 Blood
Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels. Abstract

Carmeliet, Peter

Vesalius Research Center, Vlaams Iustituut voor Biotechnologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, Leuven 07/14/2010 9.90 Blood
Role of synectin in lymphatic development in zebrafish and frogs. Abstract

Ruhrberg, Christiana

University College London 04/19/2010 9.90 Blood
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Abstract

Kahn, Mark L

University of Pennsylvania 04/02/2010 9.90 Blood
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Abstract

Petrova, Tatiana V

Molecular and Cancer Biology Program, Biomedicum Helsinki, Helsinki 11/30/2009 9.90 Blood
Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 04/03/2009 9.90 Blood
Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 12/19/2008 9.90 Blood
Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages. Abstract

Cao, Yihai

Karolinska Institute 08/05/2013 9.81 Proceedings of the National Academy of Sciences of the United States of America
Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth. Abstract

Alitalo, Kari

University of Helsinki 07/22/2013 9.81 Proceedings of the National Academy of Sciences of the United States of America
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation. Abstract

Cao, Yihai

Karolinska Institute 07/01/2013 9.81 Proceedings of the National Academy of Sciences of the United States of America
Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 03/25/2013 9.81 Proceedings of the National Academy of Sciences of the United States of America
Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment. Abstract

Cao, Yihai

Karolinska Institute 12/24/2012 9.81 Proceedings of the National Academy of Sciences of the United States of America
Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs. Abstract

Cao, Yihai

Karolinska Institute 09/11/2012 9.81 Proceedings of the National Academy of Sciences of the United States of America
Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis. Abstract

Carmeliet, Peter

University of Leuven 07/29/2011 9.81 Proceedings of the National Academy of Sciences of the United States of America
VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 12/20/2010 9.81 Proceedings of the National Academy of Sciences of the United States of America
C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Abstract

Alitalo, Kari

University of Helsinki 02/10/2010 9.81 Proceedings of the National Academy of Sciences of the United States of America
Structural determinants of growth factor binding and specificity by VEGF receptor 2. Abstract

Johnson, Randall S

University of California 02/08/2010 9.81 Proceedings of the National Academy of Sciences of the United States of America
Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Abstract

Cao, Yihai

Karolinska Institute 12/22/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathy. Abstract

Cao, Yihai

Karolinska Institute 11/03/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 10/19/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. Abstract

Cao, Yihai

Karolinska Institutet 10/12/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
Nitric oxide permits hypoxia-induced lymphatic perfusion by controlling arterial-lymphatic conduits in zebrafish and glass catfish. Abstract

Cao, Yihai

Karolinska Institute 09/25/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
Malignant cell-derived PlGF promotes normalization and remodeling of the tumor vasculature. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 04/03/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Abstract

Mooney, David J

Harvard University 01/06/2009 9.81 Proceedings of the National Academy of Sciences of the United States of America
Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 06/20/2012 9.49 Circulation research
An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation. Abstract

Alitalo, Kari

University of Helsinki 05/14/2009 9.49 Circulation research
Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Abstract

Alitalo, Kari

University of Helsinki 09/01/2013 9.40 Cold Spring Harbor perspectives in biology
Receptor tyrosine kinase-mediated angiogenesis. Abstract

Kiefer, Friedemann

Max Planck Institute for Molecular Biomedicine 01/08/2013 9.21 The EMBO journal
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. Abstract

Lammert, Eckhard

Heinrich-Heine University 12/13/2011 9.21 The EMBO journal
Mechanoinduction of lymph vessel expansion. Abstract

Hong, Young-Kwon

University of Southern California 08/12/2010 9.13 PLoS pathogens
Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. Abstract

Carmeliet, Peter

University of Leuven 09/27/2013 8.56 Pharmacology & therapeutics
Bevacizumab and micrometastases: revisiting the preclinical and clinical rollercoaster. Abstract

Choueiri, Toni K

Stanford University School of Medicine 02/01/2011 8.49 European urology
Comparison of four early posttherapy imaging changes (EPTIC; RECIST 1.0, tumor shrinkage, computed tomography tumor density, Choi criteria) in assessing outcome to vascular endothelial growth factor-targeted therapy in patients with advanced renal cell carcinoma. Abstract

Carmeliet, Peter

University of Leuven 11/22/2010 8.09 Current opinion in genetics & development
Vessel abnormalization: another hallmark of cancer? Molecular mechanisms and therapeutic implications. Abstract

Simons, Michael

Yale University School of Medicine 08/09/2012 7.95 Physiology (Bethesda, Md.)
An inside view: VEGF receptor trafficking and signaling. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 10/20/2011 7.95 Physiology (Bethesda, Md.)
Ups and downs of guided vessel sprouting: the role of polarity. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 05/21/2013 7.86 Cancer research
VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis. Abstract

McDonald, Donald M

University of California 04/10/2013 7.86 Cancer research
Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic mice. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 02/25/2013 7.86 Cancer research
Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 12/14/2012 7.86 Cancer research
Endocan is upregulated on tumor vessels in invasive bladder cancer where it mediates VEGF-A-induced angiogenesis. Abstract

Alitalo, Kari

University of Helsinki 05/16/2012 7.86 Cancer research
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth. Abstract

Johnson, Randall S

University of California 05/03/2012 7.86 Cancer research
Loss of fibroblast HIF-1α accelerates tumorigenesis. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 04/17/2012 7.86 Cancer research
Anti-VEGF/VEGFR therapy for cancer: reassessing the target. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 09/21/2011 7.86 Cancer research
Tumor-surrogate blood vessel subtypes exhibit differential susceptibility to anti-VEGF therapy. Abstract

Stacker, Steven A

Royal Melbourne Hospital 08/25/2011 7.86 Cancer research
A role for bone morphogenetic protein-4 in lymph node vascular remodeling and primary tumor growth. Abstract

Sood, Anil K

University of Texas M.D. Anderson Cancer Center 07/27/2011 7.86 Cancer research
Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer. Abstract

McDonald, Donald M

University of California 03/02/2011 7.86 Cancer research
Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 01/04/2011 7.86 Cancer research
Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 11/30/2010 7.86 Cancer research
Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 10/26/2010 7.86 Cancer research
In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 09/07/2010 7.86 Cancer research
Quantitative imaging of lymphatic function with liposomal indocyanine green. Abstract

McDonald, Donald M

University of California 03/02/2010 7.86 Cancer research
Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth. Abstract

Liu, Mingyao

East China Normal University 02/16/2010 7.86 Cancer research
Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 10/13/2009 7.86 Cancer research
Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. Abstract

Liu, Mingyao

East China Normal University 08/11/2009 7.86 Cancer research
Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation. Abstract

Liu, Mingyao

East China Normal University 06/30/2009 7.86 Cancer research
Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 05/12/2009 7.86 Cancer research
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Abstract

McDonald, Donald M

University of California 04/28/2009 7.86 Cancer research
Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 04/07/2009 7.86 Cancer research
The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 12/11/2009 7.81 Cytokine & growth factor reviews
Pathways mediating VEGF-independent tumor angiogenesis. Abstract

Alitalo, Kari

University of Helsinki 02/10/2011 7.80 Science translational medicine
Photodynamic ablation of lymphatic vessels and intralymphatic cancer cells prevents metastasis. Abstract

Ellis, Lee M

The University of Texas MD Anderson Cancer Center 04/02/2013 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
Predictive biomarkers for bevacizumab: are we there yet? Abstract

Luo, Yongzhang

Tsinghua University 08/29/2012 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. Abstract

Heymach, John V

The University of Texas M. D. Anderson Cancer Center 06/01/2011 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept. Abstract

Ellis, Lee M

The University of Texas MD Anderson Cancer Center 11/03/2009 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Abstract

Carmeliet, Peter

University of Leuven 05/26/2009 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
"Antimyeloangiogenic" therapy for cancer by inhibiting PlGF. Abstract

Heymach, John V

The University of Texas M. D. Anderson Cancer Center 05/15/2009 7.74 Clinical cancer research : an official journal of the American Association for Cancer Research
Baseline vascular endothelial growth factor concentration as a potential predictive marker of benefit from vandetanib in non-small cell lung cancer. Abstract

Alitalo, Kari

University of Helsinki 07/02/2013 7.50 Science signaling
The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 04/16/2013 7.50 Science signaling
Phosphoproteomic analysis implicates the mTORC2-FoxO1 axis in VEGF signaling and feedback activation of receptor tyrosine kinases. Abstract

Cao, Yihai

Karolinska Institute 02/24/2009 7.50 Science signaling
Positive and negative modulation of angiogenesis by VEGFR1 ligands. Abstract

Zhang, Yuanyuan

Wake Forest School of Medicine 08/09/2013 7.40 Biomaterials
The effect of urine-derived stem cells expressing VEGF loaded in collagen hydrogels on myogenesis and innervation following after subcutaneous implantation in nude mice. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 04/06/2013 7.40 Biomaterials
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 05/03/2012 7.40 Biomaterials
Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles. Abstract

Dai, Jianwu

Chinese Academy of Sciences 11/24/2010 7.40 Biomaterials
Regeneration of full-thickness abdominal wall defects in rats using collagen scaffolds loaded with collagen-binding basic fibroblast growth factor. Abstract

Dai, Jianwu

Chinese Academy of Sciences 10/18/2010 7.40 Biomaterials
The promotion of neural regeneration in an extreme rat spinal cord injury model using a collagen scaffold containing a collagen binding neuroprotective protein and an EGFR neutralizing antibody. Abstract

Mooney, David J

Harvard University 08/25/2010 7.40 Biomaterials
Modulating Notch signaling to enhance neovascularization and reperfusion in diabetic mice. Abstract

Dai, Jianwu

Chinese Academy of Sciences 08/15/2010 7.40 Biomaterials
The promotion of neurological recovery in the rat spinal cord crushed injury model by collagen-binding BDNF. Abstract

Mooney, David J

Harvard University 11/10/2009 7.40 Biomaterials
Effects of VEGF temporal and spatial presentation on angiogenesis. Abstract

Dai, Jianwu

Chinese Academy of Sciences 07/01/2009 7.40 Biomaterials
The effect of collagen-binding NGF-beta on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model. Abstract

Mooney, David J

Harvard University 05/29/2009 7.40 Biomaterials
Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. Abstract

Zhang, Yun

Shandong University 04/03/2008 7.08 International journal of cardiology
Lymphangiogenesis promotes inflammation and neointimal hyperplasia after adventitia removal in the rat carotid artery. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 10/23/2012 6.87 Molecular therapy : the journal of the American Society of Gene Therapy
AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy. Abstract

Ruhrberg, Christiana

University College London 01/11/2013 6.65 Seminars in cell & developmental biology
Neuropilin signalling in vessels, neurons and tumours. Abstract

Ruhrberg, Christiana

University College London 03/21/2012 6.60 Development (Cambridge, England)
Diverse roles for VEGF-A in the nervous system. Abstract

Ruhrberg, Christiana

University College London 08/18/2011 6.60 Development (Cambridge, England)
The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins. Abstract

Ruhrberg, Christiana

University College London 08/10/2011 6.60 Development (Cambridge, England)
VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Abstract

Mercurio, Arthur M

University of Massachusetts Medical School 06/22/2011 6.60 Development (Cambridge, England)
Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland. Abstract

Hodivala-Dilke, Kairbaan M

Bart's & The London Queen Mary's School of Medicine & Dentistry 11/12/2009 6.60 Development (Cambridge, England)
Regulation of lymphatic-blood vessel separation by endothelial Rac1. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 01/28/2009 6.60 Development (Cambridge, England)
Neurovascular development uses VEGF-A signaling to regulate blood vessel ingression into the neural tube. Abstract

Lammert, Eckhard

Heinrich-Heine University 05/12/2013 6.57 Cellular and molecular life sciences : CMLS
Mechanical forces in lymphatic vascular development and disease. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 03/12/2013 6.57 Cellular and molecular life sciences : CMLS
Neurovascular development and links to disease. Abstract

Wang, Yingqun

Zhongda Hospital Affiliated to Southeast University 01/26/2010 6.57 Cellular and molecular life sciences : CMLS
Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer's disease. Abstract

Choueiri, T K

University of Calgary 11/05/2011 6.43 Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy. Abstract

Choueiri, T K

University of Calgary 11/29/2010 6.43 Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes. Abstract

Zhang, Y

Institutes of Medical Sciences 07/15/2013 6.37 Oncogene
Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma. Abstract

Detmar, M

Swiss Federal Institute of Technology 12/19/2011 6.37 Oncogene
Interaction of tumor cells and lymphatic vessels in cancer progression. Abstract

Ellis, L M

The University of Texas MD Anderson Cancer Center 11/08/2010 6.37 Oncogene
Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells. Abstract

Heymach, J V

The University of Texas MD Anderson Cancer Center 03/08/2010 6.37 Oncogene
Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 06/06/2013 6.37 Arteriosclerosis, thrombosis, and vascular biology
Flt-1 (vascular endothelial growth factor receptor-1) is essential for the vascular endothelial growth factor-Notch feedback loop during angiogenesis. Abstract

Kahn, Mark L

University of Pennsylvania 11/11/2010 6.37 Arteriosclerosis, thrombosis, and vascular biology
Platelets: covert regulators of lymphatic development. Abstract

Alitalo, Kari

University of Helsinki 11/12/2009 6.37 Arteriosclerosis, thrombosis, and vascular biology
Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 05/21/2009 6.37 Arteriosclerosis, thrombosis, and vascular biology
Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 01/22/2009 6.37 Arteriosclerosis, thrombosis, and vascular biology
Vascular endothelial growth factor. Abstract

Carmeliet, P

Vesalius Research Center, KU Leuven, Leuven 04/15/2008 6.37 Journal of medical genetics
Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 07/03/2012 6.32 The Journal of pathology
Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors. Abstract

Luo, Yongzhang

Tsinghua University 09/27/2010 6.32 The Journal of pathology
Endostatin inhibits tumour lymphangiogenesis and lymphatic metastasis via cell surface nucleolin on lymphangiogenic endothelial cells. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 11/13/2008 6.31 The Journal of investigative dermatology
Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 03/07/2012 6.11 Journal of cell science
Role of shear-stress-induced VEGF expression in endothelial cell survival. Abstract

Mercurio, Arthur M

University of Massachusetts Medical School 02/02/2012 6.11 Journal of cell science
Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 06/10/2013 6.06 Cardiovascular research
The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 04/14/2011 6.06 Cardiovascular research
Epigenetic regulation of key vascular genes and growth factors. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 12/02/2009 6.06 Cardiovascular research
The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice. Abstract

Carmeliet, Peter

University of Leuven 12/01/2009 6.06 Cardiovascular research
Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 11/09/2013 6.06 Angiogenesis
Lymphatic vessels: new targets for the treatment of inflammatory diseases. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 01/17/2013 6.06 Angiogenesis
Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 09/09/2012 6.06 Angiogenesis
Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations. Abstract

Luo, Yongzhang

Tsinghua University 06/19/2012 6.06 Angiogenesis
The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells. Abstract

Adams, Ralf H

University of Münster 02/12/2009 6.06 Angiogenesis
Molecular differentiation and specialization of vascular beds. Abstract

Ribatti, Domenico

University of Bari Medical School 03/23/2011 6.05 Cancer treatment reviews
Novel angiogenesis inhibitors: addressing the issue of redundancy in the angiogenic signaling pathway. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 02/26/2013 5.95 Neoplasia (New York, N.Y.)
Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45A. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 07/12/2013 5.91 Nanoscale
VEGF-loaded graphene oxide as theranostics for multi-modality imaging-monitored targeting therapeutic angiogenesis of ischemic muscle. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 08/01/2011 5.83 Chemistry & biology
Size effect in molecular imaging of vascular endothelial growth factor. Abstract

Luo, Yongzhang

Tsinghua University 01/22/2010 5.79 Journal of immunology (Baltimore, Md. : 1950)
NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 05/09/2013 5.73 Journal of controlled release : official journal of the Controlled Release Society
Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. Abstract

Carmeliet, P

Vesalius Research Center, KU Leuven, Leuven 10/25/2008 5.73 Journal of thrombosis and haemostasis : JTH
Development of targeted angiogenic medicine. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 10/23/2008 5.73 Stroke; a journal of cerebral circulation
Positron emission tomography imaging of poststroke angiogenesis. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 05/16/2013 5.71 FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 11/08/2011 5.71 FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 04/16/2010 5.71 FASEB journal : official publication of the Federation of American Societies for Experimental Biology
RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. Abstract

Liu, Mingyao

East China Normal University 03/22/2011 5.70 Carcinogenesis
1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Abstract

Liu, Mingyao

East China Normal University 08/23/2010 5.70 Carcinogenesis
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Abstract

Zhang, Yafang

Mudanjiang Medical University 06/15/2011 5.54 European journal of cancer (Oxford, England : 1990)
RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways. Abstract

Motzer, Robert J

Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 04/08/2011 5.54 European journal of cancer (Oxford, England : 1990)
Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma. Abstract

Ribatti, Domenico

University of Bari Medical School 05/04/2009 5.54 European journal of cancer (Oxford, England : 1990)
Angiogenesis in pre-malignant conditions. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 05/17/2010 5.53 Molecular and cellular biology
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 09/29/2012 5.45 Ophthalmology
Vascular endothelial growth factor a in intraocular vascular disease. Abstract

Sood, Anil K

University of Texas M.D. Anderson Cancer Center 12/24/2008 5.44 International journal of cancer. Journal international du cancer
Functional significance of VEGFR-2 on ovarian cancer cells. Abstract

Wang, Yaohe

Queen Mary University of London 12/26/2012 5.40 Journal of virology
Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway. Abstract

Cao, Yihai

Karolinska Institute 01/16/2013 5.36 Cell cycle (Georgetown, Tex.)
Clock controls angiogenesis. Abstract

Cao, Yihai

Karolinska Institute 05/15/2010 5.36 Cell cycle (Georgetown, Tex.)
Cancer-associated retinopathy: a new mechanistic insight on vascular remodeling. Abstract

Cao, Yihai

Karolinska Institute 03/06/2010 5.36 Cell cycle (Georgetown, Tex.)
Pathological angiogenesis facilitates tumor cell dissemination and metastasis. Abstract

Ribatti, Domenico

University of Bari Medical School 12/28/2012 5.27 Critical reviews in oncology/hematology
Anti-angiogenesis in neuroblastoma. Abstract

Liu, Mingyao

East China Normal University 12/27/2011 5.23 Molecular cancer therapeutics
Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Abstract

Liu, Mingyao

East China Normal University 03/03/2011 5.23 Molecular cancer therapeutics
(-)-Gossypol suppresses the growth of human prostate cancer xenografts via modulating VEGF signaling-mediated angiogenesis. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 12/24/2009 5.22 PLoS computational biology
The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 05/01/2012 5.09 The AAPS journal
Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms. Abstract

Ellis, L M

The University of Texas MD Anderson Cancer Center 03/15/2011 5.04 British journal of cancer
Chronic exposure of colorectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration. Abstract

Dvorak, H F

Beth Israel Deaconess Medical Center and Harvard Medical School 02/24/2009 5.04 British journal of cancer
Why are tumour blood vessels abnormal and why is it important to know? Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 02/26/2010 4.94 Molecular biology of the cell
Binding to the extracellular matrix and proteolytic processing: two key mechanisms regulating vascular endothelial growth factor action. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 11/01/2012 4.94 Disease models & mechanisms
Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice. Abstract

McDonald, Donald M

University of California 02/04/2013 4.89 The American journal of pathology
Transgenic overexpression of interleukin-1β induces persistent lymphangiogenesis but not angiogenesis in mouse airways. Abstract

Lemström, Karl B

FI-00014 University of Helsinki and Helsinki University Central Hospital 09/07/2012 4.89 The American journal of pathology
Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 06/29/2012 4.89 The American journal of pathology
A brief history of anti-VEGF for the treatment of ocular angiogenesis. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 12/23/2011 4.89 The American journal of pathology
Inflammation-induced lymph node lymphangiogenesis is reversible. Abstract

McDonald, Donald M

University of California 10/15/2010 4.89 The American journal of pathology
Angiopoietin-2-driven vascular remodeling in airway inflammation. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 07/16/2010 4.89 The American journal of pathology
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. Abstract

McDonald, Donald M

University of California 02/25/2010 4.89 The American journal of pathology
Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels. Abstract

Liu, Mingyao

East China Normal University 02/18/2010 4.89 The American journal of pathology
Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability. Abstract

McDonald, Donald M

University of California 02/04/2010 4.89 The American journal of pathology
Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation. Abstract

McDonald, Donald M

University of California-San Francisco 01/21/2010 4.89 The American journal of pathology
Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways. Abstract

McDonald, Donald M

University of California 10/08/2009 4.89 The American journal of pathology
Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 09/17/2009 4.89 The American journal of pathology
Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 09/03/2009 4.89 The American journal of pathology
Vascular permeability and pathological angiogenesis in caveolin-1-null mice. Abstract

McDonald, Donald M

University of California-San Francisco 05/14/2009 4.89 The American journal of pathology
alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation. Abstract

Dai, Jianwu

Chinese Academy of Sciences 10/25/2010 4.87 Acta biomaterialia
Improved cellularization and angiogenesis using collagen scaffolds chemically conjugated with vascular endothelial growth factor. Abstract

Ribatti, D

11 Policlinico 03/23/2010 4.86 Current medicinal chemistry
Targeting tumor lymphangiogenesis: an update. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 07/22/2013 4.86 Inflammatory bowel diseases
Blockade of VEGF receptor-3 aggravates inflammatory bowel disease and lymphatic vessel enlargement. Abstract

Johnson, Randall S

University of California 06/14/2010 4.82 Glia
Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. Abstract

Johnson, Randall S

University of California 12/30/2013 4.78 Oncotarget
Endothelial hypoxic metabolism in carcinogenesis and dissemination: HIF-A isoforms are a NO metastatic phenomenon. Abstract

Stacker, Steven A

Royal Melbourne Hospital 08/19/2012 4.78 Oncotarget
The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 02/02/2009 4.78 Molecular pharmaceutics
Site-specifically biotinylated VEGF(121) for near-infrared fluorescence imaging of tumor angiogenesis. Abstract

Simons, Michael

Yale University School of Medicine 11/14/2013 4.77 The Journal of biological chemistry
Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 02/23/2011 4.77 The Journal of biological chemistry
Double anti-angiogenic and anti-inflammatory protein Valpha targeting VEGF-A and TNF-alpha in retinopathy and psoriasis. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 10/16/2009 4.77 The Journal of biological chemistry
Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 04/14/2009 4.77 The Journal of biological chemistry
Novel vascular endothelial growth factor D variants with increased biological activity. Abstract

Heymach, John V

The University of Texas M. D. Anderson Cancer Center 05/04/2009 4.77 Cancer
Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinoma. Abstract

Zhang, Yun

Shandong University 02/16/2011 4.67 Journal of molecular medicine (Berlin, Germany)
Ginsenoside-Rg1 enhances angiogenesis and ameliorates ventricular remodeling in a rat model of myocardial infarction. Abstract

Dvorak, Harold F

Harvard Medical School 05/20/2010 4.52 Seminars in thrombosis and hemostasis
Heterogeneity of the tumor vasculature. Abstract

Hong, Young-Kwon

University of Southern California 05/20/2010 4.52 Seminars in thrombosis and hemostasis
Heterogeneity and plasticity of lymphatic endothelial cells. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 04/15/2010 4.52 Current opinion in hematology
Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis. Abstract

Alitalo, Kari

University of Helsinki 04/15/2010 4.52 Current opinion in hematology
How do angiopoietins Tie in with vascular endothelial growth factors? Abstract

Chen, Xi

Chinese Academy of Medical Sciences and Peking Union Medical College 09/11/2009 4.46 Stem cells and development
Lysophosphatidic acid protects mesenchymal stem cells against ischemia-induced apoptosis in vivo. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 04/24/2013 4.43 Breast cancer research and treatment
Dynamics of lymphatic regeneration and flow patterns after lymph node dissection. Abstract

Ambati, Jayakrishna

Departments of Ophthalmology & Visual Sciences, Lexington, Kentucky 10/21/2010 4.31 Annals of the New York Academy of Sciences
Soluble VEGFR-2: an antilymphangiogenic variant of VEGF receptors. Abstract

Sood, Anil K

University of Texas M.D. Anderson Cancer Center 07/07/2012 4.24 Cancer letters
Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma. Abstract

Ribatti, Domenico

University of Bari Medical School 03/22/2011 4.24 Cancer letters
The controversial role of placental growth factor in tumor growth. Abstract

Hong, Yong-Kil

The Catholic University of Korea 08/06/2009 4.24 Cancer letters
Enhancement of anti-tumor activity by low-dose combination of the recombinant urokinase kringle domain and celecoxib in a glioma model. Abstract

Wang, Yizheng

Second Military Medical University 04/24/2009 4.24 Cancer letters
Critical role of TRPC6 channels in VEGF-mediated angiogenesis. Abstract

Ribatti, Domenico

University of Bari Medical School 01/17/2009 4.24 Cancer letters
An alternative in vivo system for testing angiogenic potential of human neuroblastoma cells. Abstract

Wang, Yi

Third Military Medical University 10/17/2009 4.22 American journal of ophthalmology
Intravitreous vascular endothelial growth factor and hypoxia-inducible factor 1a in patients with proliferative diabetic retinopathy. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 12/16/2009 4.22 Human gene therapy
Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes. Abstract

Zhang, Ying

USA; Laboratory for Conservation and Utilization of Bio-resources Yunnan University 05/16/2013 4.19 Molecular and cellular endocrinology
Decursin inhibited proliferation and angiogenesis of endothelial cells to suppress diabetic retinopathy via VEGFR2. Abstract

Zhang, Yanmin

Xi'an Jiaotong University 08/02/2013 4.13 Journal of cellular and molecular medicine
Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 10/16/2009 4.13 Journal of cellular and molecular medicine
A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 07/06/2009 4.13 Journal of cellular and molecular medicine
Lymphangiogenesis and cancer metastasis. Abstract

Chen, Xiangmei

PLA General Hospital and Military Medical Postgraduate College 05/08/2013 4.09 PloS one
Rapamycin upregulates autophagy by inhibiting the mTOR-ULK1 pathway, resulting in reduced podocyte injury. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 11/08/2011 4.09 PloS one
A two-compartment model of VEGF distribution in the mouse. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 09/13/2011 4.09 PloS one
Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 08/02/2010 4.09 PloS one
Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 07/29/2010 4.09 PloS one
Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. Abstract

Hodivala-Dilke, Kairbaan M

Queen Mary University of London 03/22/2010 4.09 PloS one
Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 09/18/2009 4.09 PloS one
VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 04/08/2009 4.09 PloS one
PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 04/08/2009 4.09 PloS one
A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 03/31/2009 4.09 PloS one
Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells. Abstract

Ruhrberg, Christiana

University College London 07/10/2012 4.07 Developmental biology
NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 07/26/2011 4.07 Developmental biology
Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development. Abstract

Wang, Yan

The General Hospital of Chinese People's Liberation Army 06/02/2010 4.05 Clinical immunology (Orlando, Fla.)
Analysis of JAK2 and STAT3 polymorphisms in patients with ankylosing spondylitis in Chinese Han population. Abstract

Wang, Yan

The General Hospital of Chinese People's Liberation Army 08/01/2013 4.02 Bone
Effects of endostar combined multidrug chemotherapy in osteosarcoma. Abstract

Koh, Gou Young

Korea Advanced Institute of Science and Technology 04/11/2011 3.99 Molecular cancer
Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer. Abstract

Jain, Rakesh K

Massachusetts General Hospital and Harvard Medical School 05/18/2010 3.91 The oncologist
Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer. Abstract

Chen, Xuesi

Chinese Academy of Sciences 07/19/2013 3.89 Macromolecular bioscience
Effective tumor treatment by VEGF siRNA complexed with hydrophobic poly(amino acid)-modified polyethylenimine. Abstract

Ribatti, D

11 Policlinico 04/19/2012 3.87 Genes and immunity
Sjögren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB. Abstract

Chen, Xiaoyuan

National Institutes of Health (NIH) 07/01/2011 3.84 Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
Preclinical lymphatic imaging. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 09/11/2008 3.84 Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
Quantitative PET imaging of VEGF receptor expression. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 10/09/2012 3.79 Atherosclerosis
Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A. Abstract

Yla-Herttuala, Seppo

University of Eastern Finland 08/03/2011 3.79 Atherosclerosis
Adventitial gene transfer of VEGFR-2 specific VEGF-E chimera induces MCP-1 expression in vascular smooth muscle cells and enhances neointimal formation. Abstract

Zhang, Yanbin

Xuzhou Medical College 11/22/2012 3.77 Circulation journal : official journal of the Japanese Circulation Society
Luteolin inhibits angiotensin II-induced human umbilical vein endothelial cell proliferation and migration through downregulation of Src and Akt phosphorylation. Abstract

Zhang, Youcheng

Lanzhou University Second Hospital 11/25/2013 3.74 Cell biochemistry and biophysics
The value of expression of M2-PK and VEGF in patients with advanced gastric cancer. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 11/14/2011 3.73 The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research
The cutaneous vascular system in chronic skin inflammation. Abstract

Chen, Xiang

Kagoshima University Graduate School of Medical and Dental Sciences 01/08/2010 3.72 Journal of dermatological science
CD147/basigin promotes progression of malignant melanoma and other cancers. Abstract

Ylä-Herttuala, S

University of Eastern Finland 05/12/2011 3.71 Gene therapy
Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle. Abstract

Ylä-Herttuala, S

University of Eastern Finland 02/12/2009 3.71 Gene therapy
Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 04/09/2010 3.71 American journal of physiology. Heart and circulatory physiology
VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 10/04/2010 3.68 Wiley interdisciplinary reviews. Systems biology and medicine
Systems biology of pro-angiogenic therapies targeting the VEGF system. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 11/07/2012 3.66 Investigative ophthalmology & visual science
Expression and role of VEGF--a in the ciliary body. Abstract

McDonald, Denise M

Queen's University Belfast 10/03/2012 3.66 Investigative ophthalmology & visual science
eNOS overexpression exacerbates vascular closure in the obliterative phase of OIR and increases angiogenic drive in the subsequent proliferative stage. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 12/09/2011 3.66 Investigative ophthalmology & visual science
Expression and role of VEGF in the adult retinal pigment epithelium. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 08/29/2008 3.66 Investigative ophthalmology & visual science
Role of cell and matrix-bound VEGF isoforms in lens development. Abstract

Van Cutsem, Eric

University of Chicago Comprehensive Cancer Center 05/05/2013 3.61 Targeted oncology
Role of targeted agents in metastatic colorectal cancer. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 03/13/2013 3.58 Experimental cell research
Molecular mechanisms and imaging of lymphatic metastasis. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 12/23/2010 3.58 Experimental cell research
Quantification and cell-to-cell variation of vascular endothelial growth factor receptors. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 06/23/2010 3.58 Experimental cell research
Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 03/04/2009 3.58 Experimental cell research
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions. Abstract

Chen, Xiaoyuan

Stanford University School of Medicine 06/23/2010 3.55 Current drug targets
Vascular endothelial growth factor as an anti-angiogenic target for cancer therapy. Abstract

Stacker, Steven A

Royal Melbourne Hospital 04/17/2013 3.52 Clinical & experimental metastasis
Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis. Abstract

Stacker, Steven A

Royal Melbourne Hospital 11/03/2012 3.52 Clinical & experimental metastasis
Tumor location and nature of lymphatic vessels are key determinants of cancer metastasis. Abstract

Dvorak, Harold F

Beth Israel Deaconess Medical Center and Harvard Medical School 06/13/2012 3.52 Clinical & experimental metastasis
Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 02/01/2011 3.52 Annals of medicine
Vascular endothelial growth factors in retinal and choroidal neovascular diseases. Abstract

Luo, Yongzhang

Tsinghua University 06/01/2009 3.51 IUBMB life
Unraveling the mysteries of endostatin. Abstract

Ellis, Lee M

The University of Texas MD Anderson Cancer Center 04/27/2009 3.50 Seminars in oncology
Targeting tumor angiogenesis. Abstract

Luo, Yongzhang

Tsinghua University 12/08/2009 3.42 Biochemistry
The heparin binding motif of endostatin mediates its interaction with receptor nucleolin. Abstract

Zhang, Yang

Fudan University Shanghai Cancer Center 08/11/2012 3.41 The Journal of thoracic and cardiovascular surgery
Pattern of lymphatic spread in thoracic esophageal squamous cell carcinoma: A single-institution experience. Abstract

Zhang, Y

Institutes of Medical Sciences 05/18/2009 3.38 Neuroscience
An Ang1-Tie2-PI3K axis in neural progenitor cells initiates survival responses against oxygen and glucose deprivation. Abstract

Ribatti, D

11 Policlinico 04/17/2009 3.38 Neuroscience
Nerve growth factor and its receptors TrkA and p75 are upregulated in the brain of mdx dystrophic mouse. Abstract

Luo, Y

Sun Yat-Sen University 09/30/2012 3.38 Diabetes, obesity & metabolism
KH902 suppresses high glucose-induced migration and sprouting of human retinal endothelial cells by blocking VEGF and PIGF. Abstract

Luo, Y

Sun Yat-sen University 03/15/2012 3.38 Diabetes, obesity & metabolism
Effects of intravitreal injection of KH902, a vascular endothelial growth factor receptor decoy, on the retinas of streptozotocin-induced diabetic rats. Abstract

Dai, Jianwu

Chinese Academy of Sciences 05/08/2012 3.28 Journal of tissue engineering and regenerative medicine
Promotion of diabetic wound healing by collagen scaffold with collagen-binding vascular endothelial growth factor in a diabetic rat model. Abstract

Motzer, Robert J

Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 07/22/2013 3.26 Cancer journal (Sudbury, Mass.)
Novel approaches targeting the vascular endothelial growth factor axis in renal cell carcinoma. Abstract

Kiefer, Friedemann

Max-Planck-Institute for Molecular Biomedicine 11/22/2011 3.24 Biochemical Society transactions
Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 11/13/2009 3.24 Biochemical Society transactions
Gene therapy with vascular endothelial growth factors. Abstract

Ruhrberg, Christiana

University College London 11/13/2009 3.24 Biochemical Society transactions
Neuropilin ligands in vascular and neuronal patterning. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 07/13/2013 3.21 Journal of vascular surgery
Platelet-derived growth factor C promotes revascularization in ischemic limbs of diabetic mice. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 11/21/2011 3.15 BMC systems biology
Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 09/03/2008 3.11 Cell and tissue research
VEGF inhibition: insights from preclinical and clinical studies. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 07/22/2008 3.11 Cell and tissue research
Lymphatic endothelium in health and disease. Abstract

Wang, Yuping

Harbin Medical University 12/05/2013 3.05 The Journal of steroid biochemistry and molecular biology
Activation of vitamin D receptor promotes VEGF and CuZn-SOD expression in endothelial cells. Abstract

Wang, Yifeng

Third Affiliated Hospital of Guangzhou Medical College 06/05/2012 3.05 American journal of reproductive immunology (New York, N.Y. : 1989)
The role of tissue factor and protease-activated receptor 2 in endometriosis. Abstract

Zhang, Yongxue

Tongji Medical College of Huazhong University of Science and Technology 07/15/2012 3.02 Nuclear medicine and biology
Therapeutic gene expression in transduced mesenchymal stem cells can be monitored using a reporter gene. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 06/10/2010 3.02 European journal of clinical investigation
VEGF-DdeltaNdeltaC mediated angiogenesis in skeletal muscles of diabetic WHHL rabbits. Abstract

Luo, Yongming

Jiangxi University of Traditional Chinese Medicine 06/07/2011 3.01 BMC cancer
In vitro anti-angiogenic properties of LGD1069, a selective retinoid X-receptor agonist through down-regulating Runx2 expression on Human endothelial cells. Abstract

Cao, Yali

Jiangxi Breast Center Third Hospital of Nanchang 11/21/2013 2.93 Molecular biology reports
Silencing MAP3K1 expression through RNA interference enhances paclitaxel-induced cell cycle arrest in human breast cancer cells. Abstract

Motzer, Robert J

Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 11/13/2013 2.83 Cancer chemotherapy and pharmacology
Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma. Abstract

Ribatti, Domenico

University of Bari Medical School 06/03/2011 2.83 Cancer chemotherapy and pharmacology
Vascular normalization: a real benefit? Abstract

Zhang, Yafang

Mudanjiang Medical University 05/04/2011 2.83 Microvascular research
COX-2 expression is correlated with VEGF-C, lymphangiogenesis and lymph node metastasis in human cervical cancer. Abstract

Zhang, Yafang

Mudanjiang Medical University 07/23/2011 2.83 Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
Roles of VEGF-C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in colon cancer. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 08/22/2011 2.82 The International journal of developmental biology
From the discovery of vascular endothelial growth factor to the introduction of avastin in clinical trials - an interview with Napoleone Ferrara by Domenico Ribatti. Abstract

Ylä-Herttuala, S

University of Eastern Finland 09/24/2010 2.80 Cancer gene therapy
Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice. Abstract

Wang, Yaxu

Second Affiliated Hospital of Chongqing Medical University 01/09/2012 2.78 American journal of surgery
Expression of vascular endothelial growth factor-C in gastric carcinoma and the effect of its antisense gene transfection on the proliferation of human gastric cancer cell line SGC-7901. Abstract

Dai, Jianwu

Chinese Academy of Sciences 07/27/2010 2.75 Diabetes research and clinical practice
Acceleration of diabetic wound healing by collagen-binding vascular endothelial growth factor in diabetic rat model. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 04/07/2009 2.74 Physiological genomics
Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport. Abstract

Motzer, Robert J

Pfizer Oncology, 10646 Science Center Drive, La Jolla, San Diego, CA, 92121 09/06/2011 2.64 Cancer
Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma. Abstract

Choueiri, Toni K

Stanford University School of Medicine 06/29/2011 2.64 Cancer
The impact of kidney function on the outcome of metastatic renal cell carcinoma patients treated with vascular endothelial growth factor-targeted therapy. Abstract

Sood, Anil K

University of Texas M.D. Anderson Cancer Center 12/19/2009 2.64 Cancer biology & therapy
Combined anti-angiogenic therapy against VEGF and integrin alphaVbeta3 in an orthotopic model of ovarian cancer. Abstract

Mooney, David J

Harvard University 06/05/2012 2.60 Journal of periodontology
Guided bone regeneration using injectable vascular endothelial growth factor delivery gel. Abstract

Ribatti, Domenico

University of Bari Medical School 01/12/2012 2.59 Histochemistry and cell biology
Neuropilin-1 is upregulated in Sjögren's syndrome and contributes to pathological neovascularization. Abstract

Zhang, Yunhan

The First Affiliated Hospital of Zhengzhou University 11/06/2011 2.56 Journal of cancer research and clinical oncology
The effects of vascular endothelial growth factor C knockdown in esophageal squamous cell carcinoma. Abstract

Choueiri, Toni K

Stanford University School of Medicine 07/03/2012 2.55 Current oncology reports
The double edged sword of bleeding and clotting from VEGF inhibition in renal cancer patients. Abstract

Zhang, Yongbin

Ningxia Medical University 03/10/2013 2.52 Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
RNAi-mediated gene silencing of vascular endothelial growth factor-C inhibits tumor lymphangiogenesis and growth of gastric cancer in vivo in mice. Abstract

Zhang, Yufeng

Wuhan University 03/28/2011 2.51 Clinical oral implants research
Enhanced bone regeneration around dental implant with bone morphogenetic protein 2 gene and vascular endothelial growth factor protein delivery. Abstract

Yoon, Young-sup

Emory University School of Medicine 06/26/2012 2.49 Trends in cardiovascular medicine
Role of bone marrow-derived lymphatic endothelial progenitor cells for lymphatic neovascularization. Abstract

Kerbel, Robert S

University of Toronto 10/21/2011 2.49 Breast (Edinburgh, Scotland)
Reappraising antiangiogenic therapy for breast cancer. Abstract

Ferrara, Napoleone

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 04/08/2011 2.48 Biochemical and biophysical research communications
Comparing protein VEGF inhibitors: In vitro biological studies. Abstract

Luo, Yongzhang

Tsinghua University 01/22/2009 2.48 Biochemical and biophysical research communications
Fibrinogen facilitates the anti-tumor effect of nonnative endostatin. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 03/20/2012 2.48 The journal of gene medicine
Endothelium-specific overexpression of human vascular endothelial growth factor-D in mice leads to increased tumor frequency and a reduced lifespan. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 01/24/2012 2.48 The journal of gene medicine
Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle. Abstract

Wang, Yuping

Harbin Medical University 03/21/2011 2.44 Reproductive sciences (Thousand Oaks, Calif.)
Altered nephrin and podoplanin distribution is associated with disturbed polarity protein PARD-3 and PARD-6 expressions in podocytes from preeclampsia. Abstract

Wang, Yuping

Harbin Medical University 06/15/2009 2.44 Reproductive sciences (Thousand Oaks, Calif.)
Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia. Abstract

Wang, Yan

The General Hospital of Chinese People's Liberation Army 08/29/2012 2.43 Experimental and molecular pathology
Hypoxia inhibits the differentiation of mesenchymal stem cells into osteoblasts by activation of Notch signaling. Abstract

Detmar, Michael

Swiss Federal Institute of Technology 10/16/2012 2.40 International journal of oncology
Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator. Abstract

Zhang, Yingqi

Fourth Military Medical University 09/27/2013 2.35 BMC biotechnology
Mimotope vaccination for epitope-specific induction of anti-VEGF antibodies. Abstract

Ylä-Herttuala, Seppo

University of Eastern Finland 04/20/2013 2.34 Gene
Cardiovascular gene therapy with vascular endothelial growth factors. Abstract

Punt, Cornelis J A

Radboud University Nijmegen Medical Center 04/19/2010 2.32 Clinical therapeutics
Monoclonal antibodies in the treatment of metastatic colorectal cancer: a review. Abstract

Dai, Jianwu

Chinese Academy of Sciences 07/26/2009 2.32 Journal of materials science. Materials in medicine
Loading of VEGF to the heparin cross-linked demineralized bone matrix improves vascularization of the scaffold. Abstract

Zhang, Yongzhen

Peking University Third Hospital and Key Laboratory of Cardiovascular Molecular Biology and Regulatory peptides 11/29/2012 2.22 Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Changes and significance of serum angiopoietin-2 levels in patients with coronary heart disease. Abstract

Wang, Yiqiang

Shandong Academy of Medical Sciences 04/03/2013 2.21 Molecular vision
Profiling of genes associated with the murine model of oxygen-induced retinopathy. Abstract

D'Amore, Patricia A

Schepens Eye Research Institute/Massachusett Eye and Ear 03/01/2012 2.21 Molecular vision
Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium. Abstract

Bautch, Victoria L

The University of North Carolina at Chapel Hill 10/12/2011 2.20 Cells, tissues, organs
How blood vessel networks are made and measured. Abstract

Ruhrberg, Christiana

University College London 10/04/2010 2.17 Organogenesis
VEGF in the nervous system. Abstract

Cao, Ya

the Third Xiangya Hospital of Central SouthUniversity 05/01/2012 2.15 Journal of experimental & clinical cancer research : CR
In vitro the behaviors of metastasis with suppression of VEGF in human bone metastatic LNCaP-derivative C4-2B prostate cancer cell line. Abstract

Zhang, Yuan

Jinan University 01/10/2013 2.14 Medical oncology (Northwood, London, England)
The effect of Bcl-2 siRNA combined with miR-15a oligonucleotides on the growth of Raji cells. Abstract

Ribatti, Domenico

University of Bari Medical School 03/14/2013 2.11 Regulatory peptides
In vitro and in vivo angiogenic activity of osteoarthritic and osteoporotic osteoblasts is modulated by VEGF and vitamin D3 treatment. Abstract

Ribatti, Domenico

University of Bari Medical School 08/25/2011 2.11 Regulatory peptides
Urotensin-II-stimulated expression of pro-angiogenic factors in human vascular endothelial cells. Abstract

Ribatti, Domenico

University of Bari Medical School 04/10/2009 2.11 Regulatory peptides
Pro-angiogenic activity of Urotensin-II on different human vascular endothelial cell populations. Abstract

Zhang, Yejia

Thomas Jefferson University 08/04/2010 2.08 Spine
Fibronectin splicing variants in human intervertebral disc and association with disc degeneration. Abstract

Wang, Yunshan

Jinan Central Hospital Affiliated to Shandong University 05/05/2013 2.03 International orthopaedics
Dexamethasone induces osteogenesis via regulation of hedgehog signalling molecules in rat mesenchymal stem cells. Abstract

Popel, Aleksander S

Johns Hopkins University School of Medicine 11/09/2009 2.00 Methods in enzymology
Modeling of growth factor-receptor systems from molecular-level protein interaction networks to whole-body compartment models. Abstract

Zhang, Yanmin

Xi'an Jiaotong University 06/19/2012 2.00 Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie
Ta1722, an anti-angiogenesis inhibitor targeted on VEGFR-2 against human hepatoma. Abstract

Ribatti, Domenico

University of Bari Medical School 04/08/2010 2.00 Clinical and experimental medicine
VEGF expression and angiogenesis in oral squamous cell carcinoma: an immunohistochemical and morphometric study. Abstract

Ribatti, Domenico

University of Bari Medical School 12/24/2009 2.00 Clinical and experimental medicine
VEGF-A/HGF induce Prox-1 expression in the chick embryo chorioallantoic membrane lymphatic vasculature. Abstract

Ribatti, Domenico

University of Bari Medical School 10/31/2009 2.00 Clinical and experimental medicine
Intussusceptive microvascular growth in human glioma. Abstract
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