Palecek,Sean P

Institution: University of Wisconsin-Madison, USA

Top Collaborators: Lian X, Lee AG, Azarin SM, Zhu K, Hazeltine LB, Ghosh G, Larson EA, Popelka HM, De Pablo JJ, Hsiao C, Zhang J, Kamp TJ, Powers AD, Liu B, Kron SJ, Beebe DJ, Han W, Nie Y, Badur MG, Bergendahl V

Research Interests: Cell, Cells, Human, Epidermal Growth Factor, Stem Cells, Stem, Hydrogel, Kinase, Culture, Tissue, Cancer, Inhibition, Treatment, Tyrosine, Pluripotent Stem Cells, Embryonic Stem Cells, Therapeutic, Epidermal Growth Factor Receptor, Growth, Patients

Publications
Grants

Information and abstracts for author publications
Published Date	Impact	Publication
07/12/2010	25.4	Cell stem cell Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs.	Abstract
05/29/2012	9.8	Proceedings of the National Academy of Sciences of the United States of America Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.	Abstract
03/17/2013	9.6	Biotechnology advances Engineering the human pluripotent stem cell microenvironment to direct cell fate.	Abstract
02/26/2013	7.8	Stem cells (Dayton, Ohio) Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition.	Abstract
12/15/2011	7.4	Biomaterials Modulation of Wnt/β-catenin signaling in human embryonic stem cells using a 3-D microwell array.	Abstract
07/17/2009	6.4	ACS chemical biology Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms.	Abstract
08/03/2010	5.6	Biosensors & bioelectronics Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array.	Abstract
10/28/2010	5.5	Biomacromolecules Development of macroporous poly(ethylene glycol) hydrogel arrays within microfluidic channels.	Abstract
11/04/2013	4.9	Acta biomaterialia Temporal impact of substrate mechanics on differentiation of human embryonic stem cells to cardiomyocytes.	Abstract
07/20/2012	4.2	The Analyst Macroporous hydrogel micropillars for quantifying Met kinase activity in cancer cell lysates.	Abstract
03/20/2013	4.1	PloS one A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells.	Abstract
04/27/2013	3.8	Analytical and bioanalytical chemistry Multiplexed tyrosine kinase activity detection in cancer cells using a hydrogel immobilized substrate.	Abstract
03/14/2012	3	Biomedical microdevices Quantification of kinase activity in cell lysates via photopatterned macroporous poly(ethylene glycol) hydrogel arrays in microfluidic channels.	Abstract
03/20/2012	3	BMC cancer Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors.	Abstract
07/05/2009	3	Analytical biochemistry Hydrogel-based protein array for quantifying epidermal growth factor receptor activity in cell lysates.	Abstract
02/20/2012	2.6	Biochemical engineering journal Development of Scalable Culture Systems for Human Embryonic Stem Cells.	Abstract
02/24/2009	2.3	Biotechnology progress Scalable culture and cryopreservation of human embryonic stem cells on microcarriers.	Abstract

Grants Recieved by this author
Budget Start	Budget End	Grant Type	Project Cost	Project Title
9/01/2013	8/31/2014	NIH R21: Exploratory/Developmental Grants	$222,316	Shear regulated differentiation of hPSCs to brain endothelial cells
7/01/2011	6/30/2014	NIH R01: Research Project	$1,067,983	Prevention of C. Albicans Biofilms by Beta-Peptide Release From Thin Films
4/01/2011	3/31/2014	NIH R01: Research Project	$1,082,744	Regulating human pluripotent stem cell differentiation by colony confinement
5/01/2008	4/30/2012	NIH R01: Research Project	$829,399	Copolymer hydrogel microspheres for analysis of kinase activity in cell lysates
5/01/2008	3/31/2011	NIH R01: Research Project	$964,156	Regulating Embryonic Stem Cell Growth &Differentiation by Colony Confinement