Showing search results for "LeRoith D"
Mount Sinai School of Medicine, USA
Insulin, Cancer, Growth, Mice, Risk, Mouse, Tumor, Hyperinsulinemia,
, Obesity, Cells, Breast,
, Mortality, Glucose, Role, Muscle, Phosphorylation, Igf-1
Information and abstracts for author publications
Is growth hormone resistance/IGF-1 reduction good for you?
The Journal of clinical investigation
Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice.
Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration.
Insulin receptor phosphorylation by endogenous insulin or the insulin analog AspB10 promotes mammary tumor growth independent of the IGF-I receptor.
Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression.
Trends in endocrinology and metabolism: TEM
The proliferating role of insulin and insulin-like growth factors in cancer.
Effect of case-based training for medical residents on inpatient glycemia.
Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.
Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus.
Journal of mammary gland biology and neoplasia
Insulin and IGFs in obesity-related breast cancer.
Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation.
Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia.
Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism.
Breast cancer research : BCR
Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes.
The journals of gerontology. Series A, Biological sciences and medical sciences
Insulin-like growth factors and insulin: at the crossroad between tumor development and longevity.
Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury.
Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice.
Elevated circulating IGF-I promotes mammary gland development and proliferation.
Minireview: IGF, Insulin, and Cancer.
Obesity, type 2 diabetes, and cancer: the insulin and IGF connection.
Hyperinsulinemia promotes metastasis to the lung in a mouse model of Her2-mediated breast cancer.
Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes.
Annals of the New York Academy of Sciences
Diabetes, cancer, and metformin: connections of metabolism and cell proliferation.
Molecular and cellular endocrinology
Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways.
Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation.
Intracerebroventricular leptin infusion improves glucose homeostasis in lean type 2 diabetic MKR mice via hepatic vagal and non-vagal mechanisms.
Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis.
Current opinion in endocrinology, diabetes, and obesity
Diabetes, antihyperglycemic medications and cancer risk: smoke or fire?
Diabetes/metabolism research and reviews
Can endogenous hyperinsulinaemia explain the increased risk of cancer development and mortality in type 2 diabetes: evidence from mouse models.
Diabetes/metabolism research and reviews
The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes.
Diabetes, glucose control, glucose lowering medications, and cancer risk: a 10-year population-based historical cohort.
International journal of biological sciences
The link between the metabolic syndrome and cancer.
Current diabetes reports
Insulin, insulin resistance, obesity, and cancer.
Vitamins and hormones
The epidemiology and molecular mechanisms linking obesity, diabetes, and cancer.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme
The effect of leptin administration on mammary tumor growth in diabetic mice.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Biological effects of growth hormone on carbohydrate and lipid metabolism.
The Mount Sinai journal of medicine, New York
Type 2 diabetes and cancer: what is the connection?
Grants Recieved by this author
R01: Research Project
Insulin Resistance and Breast Cancer Prognosis in Black &White Women
R01: Research Project
Mechanisms for Increased Breast Cancer Risk in Type 2 Diabetes
Construction of a Multilayered Mesenchymal Stem Cell Sheet with a 3D Dynamic Culture System
Construction of a Multilayered…
Method for Evaluating the Gut-Blood Barrier and Liver Metabolism of Microbiota Products
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
Scalable Fabrication of Stretc…
Detection of Heterodimerization of Protein Isoforms Using an
Proximity Ligation Assay
Detection of Heterodimerizatio…
Preparation of Chloroplast Sub-compartments from Arabidopsis for the Analysis of Protein Localization by Immunoblotting or Proteomics
Preparation of Chloroplast Sub…
Capture and Identification of RNA-binding Proteins by Using Click Chemistry-assisted RNA-interactome Capture (CARIC) Strategy
Capture and Identification of …
Model for the Evaluation of Endoscopic Submucosal Injection Material Performance
Time-lapse 3D Imaging of Phagocytosis by Mouse Macrophages
Time-lapse 3D Imaging of Phago…
Approaches to Determine Intestinal Epithelial Cell Permeability
Real-time Imaging and Quantification of Fungal Biofilm Development Using a Two-Phase Recirculating Flow System
Real-time Imaging and Quantifi…
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