Showing search results for "Jean-Claude BJ"
Epidermal Growth Factor
, Cells, Growth, DNA, Human, Cell,
Epidermal Growth Factor Receptor
, Apoptosis, Cancer, Phosphorylation, Tumor, Breast,
, Kinase, Inhibition, Cytidine, Ribose, Thymidine
Information and abstracts for author publications
Journal of medicinal chemistry
Synthesis and uptake of fluorescence-labeled Combi-molecules by P-glycoprotein-proficient and -deficient uterine sarcoma cells MES-SA and MES-SA/DX5.
Molecular cancer therapeutics
Subcellular distribution of a fluorescence-labeled combi-molecule designed to block epidermal growth factor receptor tyrosine kinase and damage DNA with a green fluorescent species.
Breast cancer research and treatment
Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.
Molecular cancer research : MCR
MGMT is a molecular determinant for potency of the DNA-EGFR-combi-molecule ZRS1.
The Journal of pharmacology and experimental therapeutics
The combi-targeting concept: selective targeting of the epidermal growth factor receptor- and Her2-expressing cancer cells by the complex combi-molecule RB24.
"Combi-targeting" mitozolomide: conferring novel signaling inhibitory properties to an abandoned DNA alkylating agent in the treatment of advanced prostate cancer.
Investigational new drugs
ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity.
Journal of neuro-oncology
Receptor activation and inhibition in cellular response to chemotherapeutic combinational mimicries: the concept of divergent targeting.
Enhancement of the cytotoxic potential of the mixed EGFR and DNA-targeting 'combi-molecule' ZRBA1 against human solid tumour cells by a bis-quinazoline-based drug design approach.
Chemical biology & drug design
Biological effects of AL622, a molecule rationally designed to release an EGFR and a c-Src kinase inhibitor.
Real-time Imaging and Quantification of Fungal Biofilm Development Using a Two-Phase Recirculating Flow System
Real-time Imaging and Quantifi…
Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading
Eye-tracking to Distinguish Co…
Adult Zebrafish Injury Models to Study the Effects of Prednisolone in Regenerating Bone Tissue
Adult Zebrafish Injury Models …
Two-photon Imaging of Cortical Neurons in Neonatal Mice
Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates
Contractions of Human-iPSC-der…
Mouse Models Of
Infection And Gastric Pathologies
Mouse Models Of
Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds
Using Cyclic Voltammetry, UV-V…
Growing Magnetotactic Bacteria of the Genus
: Strains MSR-1, AMB-1 and MS-1
Growing Magnetotactic Bacteria…
Whole Body Vibration Methods with Survivors of Polio
Whole Body Vibration Methods w…
Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats
Sub-acute Cerebral Microhemorr…
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