Showing search results for "Donehower LA"
Baylor College of Medicine, USA
, Cancer, Cell, Tumor, Cells,
, Human, Apoptosis, Radiation, Phosphorylation, Serine, Gene, Mouse, Aging, Phenotypes, Senescence, Tissues, Cancers
Information and abstracts for author publications
Cold Spring Harbor perspectives in biology
Using mice to examine p53 functions in cancer, aging, and longevity.
MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.
Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
The Journal of pathology
Effects of TP53 mutational status on gene expression patterns across 10 human cancer types.
Cell cycle (Georgetown, Tex.)
Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.
Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency.
The Journal of biological chemistry
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
Molecular cancer research : MCR
Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses.
The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair.
Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression.
Mechanisms of ageing and development
Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.
Grants Recieved by this author
T32: Institutional National Research Service Award
Biology of Aging Training Grant
R01: Research Project
Oncogenic Function of a P53-Induced Phosphatase
R21: Exploratory/Developmental Grants
The effects of Age on Cancer Signaling Pathways in Mice
Real-time Imaging and Quantification of Fungal Biofilm Development Using a Two-Phase Recirculating Flow System
Real-time Imaging and Quantifi…
Eye-tracking to Distinguish Comprehension-based and Oculomotor-based Regressive Eye Movements During Reading
Eye-tracking to Distinguish Co…
Adult Zebrafish Injury Models to Study the Effects of Prednisolone in Regenerating Bone Tissue
Adult Zebrafish Injury Models …
Two-photon Imaging of Cortical Neurons in Neonatal Mice
Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates
Contractions of Human-iPSC-der…
Mouse Models Of
Infection And Gastric Pathologies
Mouse Models Of
Using Cyclic Voltammetry, UV-Vis-NIR, and EPR Spectroelectrochemistry to Analyze Organic Compounds
Using Cyclic Voltammetry, UV-V…
Growing Magnetotactic Bacteria of the Genus
: Strains MSR-1, AMB-1 and MS-1
Growing Magnetotactic Bacteria…
Whole Body Vibration Methods with Survivors of Polio
Whole Body Vibration Methods w…
Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats
Sub-acute Cerebral Microhemorr…
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