Cowell,John K

Institution: Georgia Regents University Cancer Center, USA

Top Collaborators: Ren M, Teng Y, Qin H, Sharma S, Hawthorn L, Ren R, Silva J, Mei Y, Yu YE, Kunapuli P, Ngoka L, Ghoshal P, Lesoon LA, Nagarajan L, Hughes B, Tidwell JA, Natarajan L, Liu M, Kitamura E, Polakiewicz R

Research Interests: Gene, Fibroblast Growth Factor, Leukemia, Human, Cancer, Cells, Disease, Kinase, Mice, Cell, Epilepsy, Lymphoma, Regulation, Stem Cells, Metastasis, Phenotype, Proteins, Bone, Bone Marrow, Fibroblast

Publications
Grants

Information and abstracts for author publications
Published Date	Impact	Publication
06/08/2009	9.9	Blood Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.	Abstract
04/28/2011	9.9	Blood Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.	Abstract
06/18/2013	9.9	Blood Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.	Abstract
07/11/2012	9.6	Leukemia Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities.	Abstract
09/21/2011	7.9	Cancer research Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases.	Abstract
02/03/2010	7.6	Human molecular genetics Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability.	Abstract
01/14/2013	6.4	Oncogene WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells.	Abstract
05/14/2013	5.7	Carcinogenesis Critical role of the WASF3 gene in JAK2/STAT3 regulation of cancer cell motility.	Abstract
05/05/2011	5.4	International journal of cancer. Journal international du cancer Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells.	Abstract
05/30/2012	5.4	International journal of cancer. Journal international du cancer HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions.	Abstract
08/17/2010	5	British journal of cancer Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases.	Abstract
02/07/2012	4.8	The Journal of biological chemistry HSP90 and HSP70 proteins are essential for stabilization and activation of WASF3 metastasis-promoting protein.	Abstract
08/26/2009	4.5	Proteomics Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.	Abstract
06/06/2012	4.1	PloS one Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage.	Abstract
04/22/2011	4.1	PloS one Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization.	Abstract
09/16/2011	4.1	PloS one Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.	Abstract
05/13/2011	3	BMC neuroscience The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development.	Abstract
10/14/2009	3	Genomics Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway.	Abstract
10/12/2010	2.7	Journal of neuroscience research Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.	Abstract
04/23/2009	2.5	Journal of molecular neuroscience : MN Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain.	Abstract

Grants Recieved by this author
Budget Start	Budget End	Grant Type	Project Cost	Project Title
7/31/2008	5/31/2013	NIH R01: Research Project	$1,340,186	Functional analysis of the WAVE3 gene
8/01/2008	1/31/2013	NIH R01: Research Project	$1,245,939	Genetic Analysis of Myeloproliferative Disease
6/01/2008	5/31/2010	NIH R01: Research Project	$322,322	Identification of Novel Genetic Biomarkers in Brain Tumors