Showing search results for "Brites D"
University of Lisbon, Portugal
Bilirubin, Cell, Lead, Neurons, Death, Brain, Cells,
, Role, Astrocytes, Hyperbilirubinemia, Microglia,
, Cultures, Cytokines, Glutamate, Production, Survival, Therapeutic, Guanosine
Information and abstracts for author publications
Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors.
Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination.
Neurobiology of disease
Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.
ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin.
Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways.
Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.
Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin.
Journal of neurochemistry
Dynamics of neuron-glia interplay upon exposure to unconjugated bilirubin.
Current pharmaceutical design
Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents.
Molecular medicine (Cambridge, Mass.)
N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity.
Molecular and cellular neurosciences
Selective vulnerability of rat brain regions to unconjugated bilirubin.
Bilirubin as a determinant for altered neurogenesis, neuritogenesis, and synaptogenesis.
Cross-talk between neurons and astrocytes in response to bilirubin: adverse secondary impacts.
Seminars in perinatology
Bilirubin injury to neurons and glial cells: new players, novel targets, and newer insights.
Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects.
Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
Analyzing Protein Architecture…
Small-Scale Colorimetric Assays of Intracellular Lactate and Pyruvate in the Nematode
Small-Scale Colorimetric Assay…
Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase
Efficient Purification and LC-…
Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Determination of Reproductive …
Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel
Fabricating a Kidney Cortex Ex…
Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder
Stress-Enhanced Fear Learning,…
A Silver Nanoparticle Method for Ameliorating Biliary Atresia Syndrome in Mice
A Silver Nanoparticle Method f…
Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language
Using Eye Movements Recorded i…
A Visual Guide for Studying Behavioral Defenses to Pathogen Attacks in Leaf-Cutting Ants
A Visual Guide for Studying Be…
Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing
Isolation of Adult Spinal Cord…
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